Neurobehavioral effects of acute low-dose whole-body irradiation
نویسندگان
چکیده
منابع مشابه
[Antitumor effects by low dose total body irradiation].
Total-body irradiation (TBI) with 0.02-0.25 Gy has been reported to have antitumor effects. In mice, low-dose TBI induces tumor growth delay, antimetastatic effects, suppressive effects on the incidence of spontaneous thymiclymphoma, sensitization of tumor to ionizing radiation, and decrease in TD50 value. In artificial metastasis, 0.20 Gy TBI suppressed lung metastasis when it was conducted be...
متن کاملPrevention of ischemia-reperfusion injury in mice kidneys by low-dose whole body irradiation preconditioning.
TO THE EDITOR: The article recently published by Kim and coworkers (3) is very interesting and presents a new modality for the prevention of ischemia-reperfusion (I/R) injury in the mouse kidney. The authors have reported that whole body irradiation preconditioning (IP) of the animals with an acute single dose at 8 Gray (Gy) protects the kidney more efficiently compared with fractionate doses a...
متن کاملRapid decrease in brain enkephalin content after low-dose whole-body X-irradiation of the rat.
Methionine-enkephalin (ME) contents in the hypothalamus and other rat brain structures were measured immediately after 10 or 20 cGy whole-body X-irradiation. The ME contents of homogenates of the striatum, hypothalamus, midbrain + thalamus, hindbrain and pituitary were assayed radioimmunologically with 125I. The contents of all the structures, except the pituitary, decreased significantly after...
متن کاملWhole-body low dose irradiation promotes the efficacy of conventional radiotherapy for cancer and possible mechanisms.
The purpose of the present study was to explore the possibility of establishing cancer radiotherapy protocols that could promote treatment efficacy at a reduced radiation dose. Mouse models of melanoma (B16) and Lewis lung carcinoma (LLC) were used in the experiments. Conventional local radiotherapy was combined with low dose whole-body irradiation (LDWBI) in the presence or absence of gene the...
متن کاملCIMETIDINE CAN MODIFY THE EFFECTS OF WHOLE BODY \'Y-IRRADIATION ON LY MPHOHEM ATOPOIETIC SYSTEM
The hematopoietic syndrome is anticipated when a dose of radiation greater than 100 cGy is received. The resulting clinical situation is life-threatening because of opportunistic infections and gradual decline in immune competency due to irradiation. Because of evidence of a possible immunomodulatory role for cimetidine, an antagonist of histamine H2 receptors, we studied the effects of thi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2021
ISSN: 0449-3060,1349-9157
DOI: 10.1093/jrr/rrab026